The Wolfram Quantum Framework provides a new, higher-level way to conveniently pursue quantum computing research with Wolfram Notebooks. The Framework offers a general suite of modeling capabilities for simulating quantum computation, with full integration into Mathematica and Wolfram Language. Starting from discrete quantum mechanics, the Framework provides a high-level symbolic representation of quantum bases, states, and operators. The Framework can perform measurements and is equipped with various well-known states and operators, such as Bell states and Pauli operators. Using such simulation capabilities as a foundation, one can use the Framework to model quantum circuits and algorithms.