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Learn More about
Wolfram Language
Related Pages
Related Symbols
BioSequence
BioSequenceTranscribe
BioSequenceTranslate
BioSequenceModify
SequenceAlignment
ResourceFunction
Related Categories
Life Sciences
Visualize Mutations in DNA Sequences
Example Notebook
Open in Cloud
Download Notebook
For a given DNA sequence, use
BioSequenceTranscribe
to transcribe it into an RNA sequence:
I
n
[
1
]
:
=
s
e
q
=
"
A
T
G
A
G
G
G
A
T
G
A
G
C
C
G
C
A
A
T
A
C
G
A
A
T
T
G
G
G
G
T
T
T
A
A
G
G
G
G
"
;
I
n
[
2
]
:
=
s
e
q
t
r
a
n
s
c
r
i
b
e
=
B
i
o
S
e
q
u
e
n
c
e
T
r
a
n
s
c
r
i
b
e
[
B
i
o
S
e
q
u
e
n
c
e
[
"
A
T
G
A
G
G
G
A
T
G
A
G
C
C
G
C
A
A
T
A
C
G
A
A
T
T
G
G
G
G
T
T
T
A
A
G
G
G
G
"
]
]
O
u
t
[
2
]
=
B
i
o
S
e
q
u
e
n
c
e
T
y
p
e
:
R
N
A
S
e
q
u
e
n
c
e
C
o
n
t
e
n
t
:
A
U
G
A
G
G
…
G
G
G
(
3
9
l
e
t
t
e
r
s
)
Use
BioSequenceTranslate
to translate it into the corresponding peptide sequences:
I
n
[
3
]
:
=
s
e
q
t
r
a
n
s
l
a
t
e
=
B
i
o
S
e
q
u
e
n
c
e
T
r
a
n
s
l
a
t
e
[
s
e
q
t
r
a
n
s
c
r
i
b
e
]
O
u
t
[
3
]
=
B
i
o
S
e
q
u
e
n
c
e
T
y
p
e
:
P
e
p
t
i
d
e
S
e
q
u
e
n
c
e
C
o
n
t
e
n
t
:
M
R
D
E
P
Q
…
F
K
G
(
1
3
l
e
t
t
e
r
s
)
Use the
BioSequenceMoleculePlot
f
unction from the
Wolfram Function Repository
to visualize the sequence:
I
n
[
4
]
:
=
R
e
s
o
u
r
c
e
F
u
n
c
t
i
o
n
[
"
B
i
o
S
e
q
u
e
n
c
e
M
o
l
e
c
u
l
e
P
l
o
t
"
]
[
s
e
q
t
r
a
n
s
l
a
t
e
]
O
u
t
[
4
]
=
M
e
t
A
r
g
A
s
p
G
l
u
P
r
o
G
l
n
T
y
r
L
e
u
G
l
y
P
h
e
L
y
s
Introduce a single nucleotide mutation to the above sequence:
I
n
[
5
]
:
=
m
i
s
s
e
q
=
S
t
r
i
n
g
R
e
p
l
a
c
e
P
a
r
t
[
s
e
q
,
"
C
"
,
{
2
0
,
2
0
}
]
O
u
t
[
5
]
=
A
T
G
A
G
G
G
A
T
G
A
G
C
C
G
C
A
A
T
C
C
G
A
A
T
T
G
G
G
G
T
T
T
A
A
G
G
G
G
Use the
DNAAlignmentPlot
function to illustrate the letter replacement:
I
n
[
6
]
:
=
R
e
s
o
u
r
c
e
F
u
n
c
t
i
o
n
[
"
D
N
A
A
l
i
g
n
m
e
n
t
P
l
o
t
"
]
[
s
e
q
,
m
i
s
s
e
q
]
O
u
t
[
6
]
=
A
T
G
A
G
G
G
A
T
G
A
G
C
C
G
C
A
A
T
A
T
G
A
G
G
G
A
T
G
A
G
C
C
G
C
A
A
T
A
C
C
G
A
A
T
T
G
G
G
G
T
T
T
A
A
G
G
G
G
C
G
A
A
T
T
G
G
G
G
T
T
T
A
A
G
G
G
G
Translate it into the corresponding peptide sequences:
I
n
[
7
]
:
=
m
i
s
s
e
q
t
r
a
n
s
l
a
t
e
=
B
i
o
S
e
q
u
e
n
c
e
T
r
a
n
s
l
a
t
e
[
B
i
o
S
e
q
u
e
n
c
e
[
m
i
s
s
e
q
]
]
O
u
t
[
7
]
=
B
i
o
S
e
q
u
e
n
c
e
T
y
p
e
:
P
e
p
t
i
d
e
S
e
q
u
e
n
c
e
C
o
n
t
e
n
t
:
M
R
D
E
P
Q
…
F
K
G
(
1
3
l
e
t
t
e
r
s
)
Use
SequenceAlignment
to find that tyrosine (Y) is replaced by serine (S) in the new peptide sequence:
I
n
[
8
]
:
=
S
e
q
u
e
n
c
e
A
l
i
g
n
m
e
n
t
[
s
e
q
t
r
a
n
s
l
a
t
e
[
"
S
e
q
u
e
n
c
e
S
t
r
i
n
g
"
]
,
m
i
s
s
e
q
t
r
a
n
s
l
a
t
e
[
"
S
e
q
u
e
n
c
e
S
t
r
i
n
g
"
]
]
O
u
t
[
8
]
=
{
M
R
D
E
P
Q
,
{
Y
,
S
}
,
E
L
G
F
K
G
}
Visualize the sequence:
I
n
[
9
]
:
=
R
e
s
o
u
r
c
e
F
u
n
c
t
i
o
n
[
"
B
i
o
S
e
q
u
e
n
c
e
M
o
l
e
c
u
l
e
P
l
o
t
"
]
[
m
i
s
s
e
q
t
r
a
n
s
l
a
t
e
]
O
u
t
[
9
]
=
M
e
t
A
r
g
A
s
p
G
l
u
P
r
o
G
l
n
S
e
r
L
e
u
G
l
y
P
h
e
L
y
s
Now introduce another type of mutation, inserting a single nucleotide into the sequence:
I
n
[
1
0
]
:
=
i
n
s
s
e
q
=
S
t
r
i
n
g
I
n
s
e
r
t
[
s
e
q
,
"
G
"
,
2
0
]
;
I
n
[
1
1
]
:
=
R
e
s
o
u
r
c
e
F
u
n
c
t
i
o
n
[
"
D
N
A
A
l
i
g
n
m
e
n
t
P
l
o
t
"
]
[
s
e
q
,
i
n
s
s
e
q
]
O
u
t
[
1
1
]
=
A
T
G
A
G
G
G
A
T
G
A
G
C
C
G
C
A
A
T
A
T
G
A
G
G
G
A
T
G
A
G
C
C
G
C
A
A
T
-
G
A
C
G
A
A
T
T
G
G
G
G
T
T
T
A
A
G
G
G
G
A
C
G
A
A
T
T
G
G
G
G
T
T
T
A
A
G
G
G
G
Translate it into the corresponding peptide sequence:
I
n
[
1
2
]
:
=
i
n
s
s
e
q
t
r
a
n
s
l
a
t
e
=
B
i
o
S
e
q
u
e
n
c
e
T
r
a
n
s
l
a
t
e
[
B
i
o
S
e
q
u
e
n
c
e
[
i
n
s
s
e
q
]
]
B
i
o
S
e
q
u
e
n
c
e
T
r
a
n
s
l
a
t
e
:
I
n
c
o
m
p
l
e
t
e
c
o
d
o
n
d
r
o
p
p
e
d
f
r
o
m
t
r
a
n
s
l
a
t
e
d
r
e
s
u
l
t
:
G
.
O
u
t
[
1
2
]
=
B
i
o
S
e
q
u
e
n
c
e
T
y
p
e
:
P
e
p
t
i
d
e
S
e
q
u
e
n
c
e
C
o
n
t
e
n
t
:
M
R
D
E
P
Q
…
V
.
G
(
1
3
l
e
t
t
e
r
s
)
Notice that the translated sequence includes the stop codon:
I
n
[
1
3
]
:
=
i
n
s
s
e
q
t
r
a
n
s
l
a
t
e
[
"
S
e
q
u
e
n
c
e
S
t
r
i
n
g
"
]
O
u
t
[
1
3
]
=
M
R
D
E
P
Q
.
R
I
G
V
.
G
Use
BioSequenceModify
to drop the letters from the peptide sequence after the stop letter:
I
n
[
1
4
]
:
=
B
i
o
S
e
q
u
e
n
c
e
M
o
d
i
f
y
[
i
n
s
s
e
q
t
r
a
n
s
l
a
t
e
,
"
D
r
o
p
F
r
o
m
S
t
o
p
L
e
t
t
e
r
"
]
[
"
S
e
q
u
e
n
c
e
S
t
r
i
n
g
"
]
O
u
t
[
1
4
]
=
M
R
D
E
P
Q
Create the molecular diagram:
I
n
[
1
5
]
:
=
R
e
s
o
u
r
c
e
F
u
n
c
t
i
o
n
[
"
B
i
o
S
e
q
u
e
n
c
e
M
o
l
e
c
u
l
e
P
l
o
t
"
]
[
B
i
o
S
e
q
u
e
n
c
e
M
o
d
i
f
y
[
i
n
s
s
e
q
t
r
a
n
s
l
a
t
e
,
"
D
r
o
p
F
r
o
m
S
t
o
p
L
e
t
t
e
r
"
]
]
O
u
t
[
1
5
]
=
M
e
t
A
r
g
A
s
p
G
l
u
P
r
o
G
l
n
See Also
DNAAlignmentPlot
BioSequenceMoleculePlot
Related Symbols
BioSequence
BioSequenceTranscribe
BioSequenceTranslate
BioSequenceModify
SequenceAlignment
ResourceFunction
Publisher Information
Contributed by:
Wolfram Staff
